To study the olivary input to the cerebellar nuclei (CN) we used optogenetic stimulation in transgenic mice expressing channelrhodopsin-2 (ChR2) in olivary neurons.We obtained in vivo extracellular Purkinje cell (PC) and CN recordings in anesthetized mice while stimulating the contralateral inferior olive (IO) with a blue laser (single pulse, 10 -
Fork-head box protein A1 (FOXA1) is a "pioneer factor" that is known to bind to the androgen receptor (AR) and regulate the transcription of AR-specific genes.However, the precise role of FOXA1 in prostate cancer (PC) remains unknown.In this study, we report that FOXA1 plays a critical role in PC cell proliferation.The expression of FOXA1 was highe
Coronary arteriovenous fistulas are rare anomalies resulting in abnormal communication between the coronary artery and any chamber of the heart.An Plate asymptomatic patient was referred for evaluation of her murmur.Two-dimensional and color Doppler echocardiographic evaluation revealed an enlarged left main coronary artery.A retrograde, eccentric
To study the changes of serum uric acid level which is influenced by various factors including nutrition, race, socio-economic conditions age, sex, obesity and hyper lipidemia, a wide variety of survey appeared to be performed.For this study in six large provinces of Iran out Plate of 12,524 apparently healthy individuals a total of 2,744 persons o
Background.Status of autonomic homoeostasis in hemostasic disturbances due to hemophilia needs to be studied.Objectives.To compare autonomic nervous system markers measured by heart rate variability (HRV) and blood flow variability Braces (BFV) in hemophiliacs and healthy age-matched control population using medical analyzer system.Design.Cross-sec